
Spaghetti strands twist together with juicy chicken and fresh veggies in a delightful sweet-savory blend that turns basic ingredients into a mouthwatering dinner. This Chicken Spaghetti Lo Mein brings takeout flavors right to your home without much work, making a filling dish that's both familiar and exciting.
I've tried making tons of Asian-inspired dishes at home, and this lo mein has become what my family asks for most. My husband usually grabs lo mein whenever we order takeout, but now he likes my version better. He says it's because the veggies are fresher and the noodles turn out just right.
Must-Have Ingredients
- Spaghetti Noodles: Standard spaghetti gives you just the right feel and soaks up all that yummy sauce.
- Chicken Breast: Look for thick, even pieces that'll cook up nice and tender.
- Bell Peppers: Go for bright, colorful ones that'll look pretty and add sweetness.
- Soy Sauce: Grab the low-sodium kind so your dish doesn't end up too salty.
- Hoisin Sauce: This rich, aromatic sauce creates that classic sweet-savory base you want.
Making Awesome Lo Mein
- Noodle Know-How:
- Cook your spaghetti until it's just firm to the bite, then cool it fast under cold water. This stops them from getting mushy when you mix them with the hot sauce later.
- Chicken Tips:
- Cut your chicken into thin, even strips so they cook fast and evenly. A little salt and pepper before cooking helps build flavor throughout your meal.
- Veggie Success:
- Cut all your veggies the same size so they cook evenly. You want them crisp but tender enough to blend with everything else in your stir-fry.
- Sauce Magic:
- Mix all your sauce stuff together before adding it to the pan. This way, the soy sauce, hoisin, and a bit of sesame oil blend perfectly for that real lo mein taste.

When I first tried making this, I wanted to copy my grandma's version that she learned while she lived in Hong Kong. Her secret was always to brown the garlic just a bit before adding anything else. She said it brought out those key flavors that gave the dish its special smell.
Great Side Dishes
Enjoy this tasty lo mein with crunchy veggie spring rolls and a cool cucumber salad with rice vinegar and sesame oil. Want to go all out? Add some steamed dumplings on the side.
Mix It Up
Switch things around by using shrimp instead of chicken, or go vegetarian with hearty mushrooms and extra veggies. If you like it hot, throw in some sriracha or chili oil to your sauce.
Keeping Leftovers
Pop any extra lo mein in a sealed container and it'll last up to three days. When you warm it up, add a splash of water or chicken broth to bring back the sauce and keep it from drying out.
I've made this dish so many times for family dinners and potlucks, and I've found that what makes Chicken Spaghetti Lo Mein so great is how flexible it is. Whether you follow everything to the letter or just use whatever veggies you've got in the fridge, you'll end up with a cozy, satisfying meal that brings everyone to the table.

Frequently Asked Questions
- → Can I swap spaghetti for another type of pasta?
- Sure! Use lo mein noodles, linguine, or even fettuccine if you like.
- → What can I use instead of oyster sauce?
- Try hoisin sauce mixed with Worcestershire, or soy sauce with some sugar for balance.
- → Can I prepare this dish in advance?
- Absolutely. It stores in the fridge for up to four days. Reheat in a skillet with a splash of water for best results.
- → Which vegetables work well here?
- Bell peppers, broccoli, mushrooms, snow peas, and carrots are all great. Just use whatever’s on hand!
- → How do I make this gluten-free?
- Use gluten-free pasta and replace soy sauce with tamari.